The responsibilities of the Analytical Project Manager are stated in the GCLP document, section 5.2. They are quite comparable to the ones of the study director described in GLP guidelines. Their roles are fully inclusive of the whole laboratory project, from its planning to its finalisation, far beyond the limited roles and responsibilities assigned to the analytical responsible scientist (ARS) in your CRO. The Analytical Project Manager is not responsible for confirming the GCP-compliance, as they have no involvement in the trial at sites, limited to the conditions of collating and receiving the biological samples. They can only confirm the GLP-compliance.